姓名：赵成周

工作单位：藏医药研究中心

职称/职务：副教授

E-mail: qhdxzcz2016@163.com

基本情况：

赵成周，性别，汉族，1986年11月生，甘肃省静宁县人，博士，副教授，硕士研究生导师，主要从事青藏高原特色植物活性成分合成与调节以及药理机制的研究。

科研方向：

1. 活性成分合成与调节：

课题组主要以含异喹啉生物生物碱的绿绒蒿属和紫堇属植物为研究对象，结合转录组学和代谢组学技术挖掘生物碱合成与调节的关键基因及揭示生态因素影响其合成的分子机制，通过转基因技术在模式植物拟南芥和烟草中验证特定基因的功能。

2. 药理研究：

以模式动物斑马鱼为研究材料，大规模筛选促进血管生成和抑制骨质疏松等疾病的药物或组方，并结合化学分离技术、组学技术、网络药理学、基因编辑技术揭示其发挥药效的物质基础和药理机制。

主持国家自然科学基金青年项目1项(31801281)，教育部春晖计划项目1项(Z2017056)，青海省自然科学基金1项(2017-ZJ-950Q)，在J Plant Physiol、 Biol Plant、Plant Cell Rep、Protoplasma等期刊发表学术论文10余篇。

代表性著作：

1、 Zhao CZ, Wang XM, Wang XY, Wu KL, Li P, Chang Ning, Wang JF, Wang F, Li JL, Bi YR (2015) Glucose-6-phosphate dehydrogenase and alternative oxidase are involved in the cross tolerance of highland barley to salt stress and UV-B radiation. J Plant Physiol. 2015 Jun 1;181:83-95.

2、 C. Z. Zhao, P. Li,X. M. Wang,P. Li,X. Y. Wang,F. Wang,J. F. Wang,N. Chang,Y. R. Bi. Nitrogen deprivation induces cross-tolerance of Poa annua callus to salt stress[J]. Biologia Plantarum,2016,60(3).

3、 Ping Li, Chengzhou Zhao, Yongqiang Zhang,Xiaomin Wang,Xiaoyu Wang,Jianfeng Wang,Feng Wang,Yurong Bi. Calcium alleviates cadmium-induced inhibition on root growth by maintaining auxin homeostasis in Arabidopsis seedlings[J]. Protoplasma,2016,253(1).

4、 Feng Wang,Xiaomin Wang,Chengzhou Zhao,Jianfeng Wang,Ping Li,Yanqin Dou,Yurong Bi. Alternative pathway is involved in the tolerance of highland barley to the low-nitrogen stress by maintaining the cellular redox homeostasis[J]. Plant Cell Reports,2016,35(2).

5、 Liu Z, Zhang Y, Wang J, Li P, Zhao C, Chen Y, Bi Y. Phytochrome-interacting factors PIF4 and PIF5 negatively regulate anthocyanin biosynthesis under red light in Arabidopsis seedlings. Plant Sci. 2015 Sep;238:64-72.

6、 Wang J, Zhang Y, Li Y, Wang X, Nan W, Hu Y, Zhang H, Zhao C, Wang F, Li P, Shi H, Bi Y. Endophytic microbes Bacillus sp. LZR216-regulated root development is dependent on polar auxin transport in Arabidopsis seedlings. Plant Cell Rep. 2015 Jun;34(6):1075-87.

7、 J. Wang,Y. Zhang,Y. Li,X. Wang,Z. Liu,W. Nan,C. Zhao,F. Wang,J. Ma,Y. Bi. Involvement of polar auxin transport in the inhibition of Arabidopsis seedling growth induced by Stenotrophomonas maltophilia[J]. Biologia Plantarum,2016,60(2).

8、 Jianfeng Wang,Yongqiang Zhang,Jie Jin,Qien Li,Chenzhou Zhao,Wenbin Nan,Xiaomin Wang,Rongrong Ma,Yurong Bi. An intact cytokinin-signaling pathway is required for Bacillus sp. LZR216-promoted plant growth and root system architecture altereation in Arabidopsis thaliana seedlings[J]. Plant Growth Regulation,2018,84(3).

9、 P. Li,C. Z. Zhao,Y. Q. Zh and,X. M. Wang,J. F. Wang,F. Wang,Y. R. Bi. Silicon enhances the tolerance of Poa annua to cadmium by inhibiting its absorption and oxidative stress[J]. Biologia Plantarum,2017,61(4).

10、任玉玲,孙胜男,王伊慧,赵成周,李萍.尼泊尔黄堇G6PDH蛋白基因的异源表达及蛋白纯化[J/OL].分子植物育种

11、东主南加,李萍,扎西东主,任玉玲,加羊洛知,王兆丰,孙胜男,赵成周.尼泊尔黄堇G6PDH基因的克隆和生物信息学分析[J/OL].分子植物育种